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Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord
BACKGROUND: Gangliosides, sialic acid-containing glycosphingolipids, are highly expressed in nervous systems of vertebrates and have been considered to be involved in the development, differentiation, and function of nervous tissues. Recent studies with gene-engineered animals have revealed that the...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986855/ https://www.ncbi.nlm.nih.gov/pubmed/24673754 http://dx.doi.org/10.1186/1742-2094-11-61 |