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Miglitol increases energy expenditure by upregulating uncoupling protein 1 of brown adipose tissue and reduces obesity in dietary-induced obese mice

BACKGROUND: Miglitol is an oral anti-diabetic drug that acts by inhibiting carbohydrate absorption in the small intestine. Recent studies have shown that miglitol reduces obesity in humans and rodents. However, its mechanisms have remained unclear. The purpose of this study was to determine whether...

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Detalles Bibliográficos
Autores principales: Sugimoto, Satoru, Nakajima, Hisakazu, Kodo, Kazuki, Mori, Jun, Matsuo, Kensuke, Kosaka, Kitaro, Aoi, Wataru, Yoshimoto, Kanji, Ikegaya, Hiroshi, Hosoi, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986880/
https://www.ncbi.nlm.nih.gov/pubmed/24669882
http://dx.doi.org/10.1186/1743-7075-11-14