Cargando…

Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to substantial neuronal damage and behavioral impairment, and Toll-like receptor 4 (TLR4) is an important mediator of thiscascade. In the current study, we tested the hypothesis that curcumin, a phytochem...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Hai-tao, Bian, Chen, Yuan, Ji-chao, Chu, Wei-hua, Xiang, Xin, Chen, Fei, Wang, Cheng-shi, Feng, Hua, Lin, Jiang-kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986937/
https://www.ncbi.nlm.nih.gov/pubmed/24669820
http://dx.doi.org/10.1186/1742-2094-11-59