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Deoxyglucose prevents neurodegeneration in culture by eliminating microglia
BACKGROUND: 2-Deoxy-d-glucose is an inhibitor of glycolysis, which is protective in animal models of brain pathology, but the mechanisms of this protection are unclear. We examined whether, when and how deoxyglucose protects neurons in co-culture with astrocytes and microglia. Microglia are brain ma...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986974/ https://www.ncbi.nlm.nih.gov/pubmed/24669778 http://dx.doi.org/10.1186/1742-2094-11-58 |