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Methylseleninic acid elevates REDD1 and inhibits prostate cancer cell growth despite AKT activation and mTOR dysregulation in hypoxia

Methylseleninic acid (MSeA) is a monomethylated selenium metabolite theoretically derived from subsequent β-lyase or transamination reactions of dietary Se-methylselenocysteine that has potent antitumor activity by inhibiting cell proliferation of several cancers. Our previous studies showed that MS...

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Detalles Bibliográficos
Autores principales: Sinha, Indu, Allen, Joshua E, Pinto, John T, Sinha, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987075/
https://www.ncbi.nlm.nih.gov/pubmed/24515947
http://dx.doi.org/10.1002/cam4.198