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Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with squamous cell carcinoma of the lung

The aim of the study was to investigate how alterations in the PI3K pathway correlate with non-small cell lung cancer subtypes squamous cell carcinoma (SSC) and adenocarcinoma (ADCA). We analyzed copy number variation and protein expression of INPP4B, protein expression of pAkt, PDPK1, and PTEN and...

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Detalles Bibliográficos
Autores principales: Stjernström, Annika, Karlsson, Christina, Fernandez, Oswaldo J, Söderkvist, Peter, Karlsson, Mats G, Thunell, Lena K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987083/
https://www.ncbi.nlm.nih.gov/pubmed/24500884
http://dx.doi.org/10.1002/cam4.191