Cargando…
Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with squamous cell carcinoma of the lung
The aim of the study was to investigate how alterations in the PI3K pathway correlate with non-small cell lung cancer subtypes squamous cell carcinoma (SSC) and adenocarcinoma (ADCA). We analyzed copy number variation and protein expression of INPP4B, protein expression of pAkt, PDPK1, and PTEN and...
Autores principales: | Stjernström, Annika, Karlsson, Christina, Fernandez, Oswaldo J, Söderkvist, Peter, Karlsson, Mats G, Thunell, Lena K |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987083/ https://www.ncbi.nlm.nih.gov/pubmed/24500884 http://dx.doi.org/10.1002/cam4.191 |
Ejemplares similares
-
pAKT pathway activation is associated with PIK3CA mutations and good prognosis in luminal breast cancer in contrast to p-mTOR pathway activation
por: Sonnenblick, Amir, et al.
Publicado: (2019) -
Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway
por: Daya, Minerva, et al.
Publicado: (2018) -
INPP4B: the New Kid on the PI3K Block
por: Agoulnik, Irina U., et al.
Publicado: (2011) -
Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers
por: Fang, Wen-Liang, et al.
Publicado: (2015) -
INPP4B restrains cell proliferation and metastasis via regulation of the PI3K/AKT/SGK pathway
por: Chen, Ying, et al.
Publicado: (2018)