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Two BRM promoter insertion polymorphisms increase the risk of early-stage upper aerodigestive tract cancers

Brahma (BRM) has a key function in chromatin remodeling. Two germline BRM promoter insertion–deletion polymorphisms, BRM-741 and BRM-1321, have been previously associated with an increased risk of lung cancer in smokers and head and neck cancer. To further evaluate their role in cancer susceptibilit...

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Detalles Bibliográficos
Autores principales: Wong, Kit Man, Qiu, Xiaoping, Cheng, Dangxiao, Azad, Abul Kalam, Habbous, Steven, Palepu, Prakruthi, Mirshams, Maryam, Patel, Devalben, Chen, Zhuo, Roberts, Heidi, Knox, Jennifer, Marquez, Stephanie, Wong, Rebecca, Darling, Gail, Waldron, John, Goldstein, David, Leighl, Natasha, Shepherd, Frances A, Tsao, Ming, Der, Sandy, Reisman, David, Liu, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987092/
https://www.ncbi.nlm.nih.gov/pubmed/24519853
http://dx.doi.org/10.1002/cam4.201