Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength

Wnt7a/Fzd7 signaling stimulates skeletal muscle growth and repair by inducing the symmetric expansion of satellite stem cells through the planar cell polarity pathway and by activating the Akt/mTOR growth pathway in muscle fibers. Here we describe a third level of activity where Wnt7a/Fzd7 increases...

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Detalles Bibliográficos
Autores principales: Bentzinger, C. Florian, von Maltzahn, Julia, Dumont, Nicolas A., Stark, Danny A., Wang, Yu Xin, Nhan, Kevin, Frenette, Jérôme, Cornelison, DDW, Rudnicki, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987134/
https://www.ncbi.nlm.nih.gov/pubmed/24711502
http://dx.doi.org/10.1083/jcb.201310035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987134/
https://www.ncbi.nlm.nih.gov/pubmed/24711502
http://dx.doi.org/10.1083/jcb.201310035

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