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Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength
Wnt7a/Fzd7 signaling stimulates skeletal muscle growth and repair by inducing the symmetric expansion of satellite stem cells through the planar cell polarity pathway and by activating the Akt/mTOR growth pathway in muscle fibers. Here we describe a third level of activity where Wnt7a/Fzd7 increases...
Autores principales: | Bentzinger, C. Florian, von Maltzahn, Julia, Dumont, Nicolas A., Stark, Danny A., Wang, Yu Xin, Nhan, Kevin, Frenette, Jérôme, Cornelison, DDW, Rudnicki, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987134/ https://www.ncbi.nlm.nih.gov/pubmed/24711502 http://dx.doi.org/10.1083/jcb.201310035 |
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