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Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation

Five endosomal sorting complexes required for transport (ESCRTs) mediate the degradation of ubiquitinated membrane proteins via multivesicular bodies (MVBs) in lysosomes. ESCRT-0, -I, and –II interact with cargo on endosomes. ESCRT-II also initiates the assembly of a ringlike ESCRT-III filament cons...

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Detalles Bibliográficos
Autores principales: Adell, Manuel Alonso Y, Vogel, Georg F., Pakdel, Mehrshad, Müller, Martin, Lindner, Herbert, Hess, Michael W., Teis, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987140/
https://www.ncbi.nlm.nih.gov/pubmed/24711499
http://dx.doi.org/10.1083/jcb.201310114