Cargando…
Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation
Five endosomal sorting complexes required for transport (ESCRTs) mediate the degradation of ubiquitinated membrane proteins via multivesicular bodies (MVBs) in lysosomes. ESCRT-0, -I, and –II interact with cargo on endosomes. ESCRT-II also initiates the assembly of a ringlike ESCRT-III filament cons...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987140/ https://www.ncbi.nlm.nih.gov/pubmed/24711499 http://dx.doi.org/10.1083/jcb.201310114 |