Cargando…

Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments

The axon initial segment (AIS) of differentiated neurons regulates action potential initiation and axon–dendritic polarity. The latter function depends on actin dynamics, but actin structure and functions at the AIS remain unclear. Using platinum replica electron microscopy (PREM), we have character...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Steven L., Korobova, Farida, Svitkina, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987141/
https://www.ncbi.nlm.nih.gov/pubmed/24711503
http://dx.doi.org/10.1083/jcb.201401045