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Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments
The axon initial segment (AIS) of differentiated neurons regulates action potential initiation and axon–dendritic polarity. The latter function depends on actin dynamics, but actin structure and functions at the AIS remain unclear. Using platinum replica electron microscopy (PREM), we have character...
Autores principales: | Jones, Steven L., Korobova, Farida, Svitkina, Tatyana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987141/ https://www.ncbi.nlm.nih.gov/pubmed/24711503 http://dx.doi.org/10.1083/jcb.201401045 |
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