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Ca(2+)–Calmodulin regulates SNARE assembly and spontaneous neurotransmitter release via v-ATPase subunit V0a1

Most chemical neurotransmission occurs through Ca(2+)-dependent evoked or spontaneous vesicle exocytosis. In both cases, Ca(2+) sensing is thought to occur shortly before exocytosis. In this paper, we provide evidence that the Ca(2+) dependence of spontaneous vesicle release may partly result from a...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Epstein, Daniel, Khalaf, Ossama, Srinivasan, Sankaranarayanan, Williamson, W. Ryan, Fayyazuddin, Amir, Quiocho, Florante A., Hiesinger, P. Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987144/
https://www.ncbi.nlm.nih.gov/pubmed/24733584
http://dx.doi.org/10.1083/jcb.201312109