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Hepatoprotective and antioxidant activity of N-acetyl cysteine in carbamazepine-administered rats

OBJECTIVES: The present study evaluates the hepatoprotective activity of N-acetyl cysteine (NAC) against carbamazepine (CBZ)-induced hepatotoxicity. MATERIALS AND METHODS: Rats were treated with CBZ (50 mg/kg p.o.) and CBZ supplemented with NAC 50, 100 and 200 mg/kg for 45 days, after which blood sa...

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Detalles Bibliográficos
Autores principales: Maheswari, Eswaran, Saraswathy, Ganesan Raja Lekshmi, Santhranii, Thakur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987193/
https://www.ncbi.nlm.nih.gov/pubmed/24741196
http://dx.doi.org/10.4103/0253-7613.129321