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Transcriptional override: a regulatory network model of indirect responses to modulations in microRNA expression
BACKGROUND: Documented changes in levels of microRNAs (miRNA) in a variety of diseases including cancer are leading to their development as early indicators of disease, and as a potential new class of therapeutic agents. A significant hurdle to the rational application of miRNAs as therapeutics is o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987680/ https://www.ncbi.nlm.nih.gov/pubmed/24666724 http://dx.doi.org/10.1186/1752-0509-8-36 |