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A Mycobacterium bovis BCG-Naked DNA Prime-Boost Vaccination Strategy Induced CD4(+) and CD8(+) T-Cell Response against Mycobacterium tuberculosis Immunogens

Mycobacterium tuberculosis infection is still a major global public health problem. Presently the only tuberculosis (TB) vaccine available is Bacille Calmette-Guérin (BCG), although it fails to adequately protect against pulmonary TB in adults. To solve this problem, the development of a new effecti...

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Detalles Bibliográficos
Autores principales: Lu, Miao, Xia, Zhi Yang, Bao, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987877/
https://www.ncbi.nlm.nih.gov/pubmed/24741595
http://dx.doi.org/10.1155/2014/395626