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Ursodeoxycholic Acid Influences the Expression of p27(kip1) but Not FoxO1 in Patients with Non-Cirrhotic Primary Biliary Cirrhosis

Background. Enhanced expression of cell cycle inhibitor p27(kip1) suppresses cell proliferation. Ursodeoxycholic acid (UDCA) delays progression of primary biliary cirrhosis (PBC) but its effect on p27(kip1) expression is uncertain. Aims. To analyze the expression of p27(kip1) and its transcription m...

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Detalles Bibliográficos
Autores principales: Milkiewicz, Malgorzata, Kopycińska, Justyna, Kempińska-Podhorodecka, Agnieszka, Haas, Tara, Bogdanos, Dimitrios P., Elias, Elwyn, Milkiewicz, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987973/
https://www.ncbi.nlm.nih.gov/pubmed/24741631
http://dx.doi.org/10.1155/2014/921285