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Dll4-Notch Signalling Blockade Synergizes Combined Ultrasound-Stimulated Microbubble and Radiation Therapy in Human Colon Cancer Xenografts

Tumour vasculature acts as an essential lifeline for tumour progression and facilitates metastatic spread. Novel vascular targeting strategies aiming to sustain vascular shutdown could potentially induce substantial damage, resulting in a significant tumour growth delay. We investigated the combinat...

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Detalles Bibliográficos
Autores principales: El Kaffas, Ahmed, Nofiele, Joris, Giles, Anoja, Cho, Song, Liu, Stanley K., Czarnota, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988033/
https://www.ncbi.nlm.nih.gov/pubmed/24736631
http://dx.doi.org/10.1371/journal.pone.0093888