In Vitro Metabolism of 20(R)-25-Methoxyl-Dammarane-3, 12, 20-Triol from Panax notoginseng in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes

The present study characterized in vitro metabolites of 20(R)-25-methoxyl-dammarane-3β, 12β, 20-triol (20(R)-25-OCH(3)-PPD) in mouse, rat, dog, monkey and human liver microsomes. 20(R)-25-OCH(3)-PPD was incubated with liver microsomes in the presence of NADPH. The reaction mixtures and the metabolit...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangrong, Zhang, Ji, Li, Wei, Liu, Li, Sun, Baoshan, Guo, Zhenghong, Shi, Caihong, Zhao, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988085/
https://www.ncbi.nlm.nih.gov/pubmed/24736630
http://dx.doi.org/10.1371/journal.pone.0094962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988085/
https://www.ncbi.nlm.nih.gov/pubmed/24736630
http://dx.doi.org/10.1371/journal.pone.0094962

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