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In Vitro Metabolism of 20(R)-25-Methoxyl-Dammarane-3, 12, 20-Triol from Panax notoginseng in Human, Monkey, Dog, Rat, and Mouse Liver Microsomes
The present study characterized in vitro metabolites of 20(R)-25-methoxyl-dammarane-3β, 12β, 20-triol (20(R)-25-OCH(3)-PPD) in mouse, rat, dog, monkey and human liver microsomes. 20(R)-25-OCH(3)-PPD was incubated with liver microsomes in the presence of NADPH. The reaction mixtures and the metabolit...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988085/ https://www.ncbi.nlm.nih.gov/pubmed/24736630 http://dx.doi.org/10.1371/journal.pone.0094962 |