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Generation and Dietary Modulation of Anti-Inflammatory Electrophilic Omega-3 Fatty Acid Derivatives

Dietary ω-3 polyunsaturated fatty acids (PUFAs) decrease cardiovascular risk via suppression of inflammation. The generation of electrophilic α,β-unsaturated ketone derivatives of the ω-3 PUFAs docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA) in activated human macrophages is catalyzed by...

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Detalles Bibliográficos
Autores principales: Cipollina, Chiara, Salvatore, Sonia R., Muldoon, Matthew F., Freeman, Bruce A., Schopfer, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988126/
https://www.ncbi.nlm.nih.gov/pubmed/24736647
http://dx.doi.org/10.1371/journal.pone.0094836