Cargando…
Generation and Dietary Modulation of Anti-Inflammatory Electrophilic Omega-3 Fatty Acid Derivatives
Dietary ω-3 polyunsaturated fatty acids (PUFAs) decrease cardiovascular risk via suppression of inflammation. The generation of electrophilic α,β-unsaturated ketone derivatives of the ω-3 PUFAs docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA) in activated human macrophages is catalyzed by...
Autores principales: | Cipollina, Chiara, Salvatore, Sonia R., Muldoon, Matthew F., Freeman, Bruce A., Schopfer, Francisco J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988126/ https://www.ncbi.nlm.nih.gov/pubmed/24736647 http://dx.doi.org/10.1371/journal.pone.0094836 |
Ejemplares similares
-
Endogenous Generation and Signaling Actions of Omega-3 Fatty Acid Electrophilic Derivatives
por: Cipollina, Chiara
Publicado: (2015) -
Olives and Olive Oil Are Sources of Electrophilic Fatty Acid Nitroalkenes
por: Fazzari, Marco, et al.
Publicado: (2014) -
Electrophilic fatty acid nitroalkenes regulate Nrf2 and NF-κB signaling:A medicinal chemistry investigation of structure-function relationships
por: Khoo, Nicholas K. H., et al.
Publicado: (2018) -
Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis
por: Jobbagy, Soma, et al.
Publicado: (2018) -
Electrophilic nitroalkene-tocopherol derivatives: synthesis, physicochemical characterization and evaluation of anti-inflammatory signaling responses
por: Rodriguez-Duarte, Jorge, et al.
Publicado: (2018)