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MiR-330-Mediated Regulation of SH3GL2 Expression Enhances Malignant Behaviors of Glioblastoma Stem Cells by Activating ERK and PI3K/AKT Signaling Pathways

MicroRNAs are currently considered as an active and rapidly evolving area for the treatment of tumors. In this study, we elucidated the biological significance of miR-330 in glioblastoma stem cells (GSCs) as well as the possible molecular mechanisms. SH3GL2 is mainly distributed in the central nervo...

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Detalles Bibliográficos
Autores principales: Yao, Yilong, Xue, Yixue, Ma, Jun, Shang, Chao, Wang, Ping, Liu, Libo, Liu, Wenjing, Li, Zhen, Qu, Shengtao, Li, Zhiqing, Liu, Yunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988141/
https://www.ncbi.nlm.nih.gov/pubmed/24736727
http://dx.doi.org/10.1371/journal.pone.0095060