A Drug Delivery Strategy: Binding Enkephalin to Asialoglycoprotein Receptor by Enzymatic Galactosylation

Glycosylation of biopharmaceuticals can mediate cell specific delivery by targeting carbohydrate receptors. Additionally, glycosylation can improve the physico-chemical (drug-like) properties of peptide based drug candidates. The main purpose of this study was to examine if glycosylation of the pept...

Descripción completa

Detalles Bibliográficos
Autores principales: Christie, Michelle P., Simerská, Pavla, Jen, Freda E.-C., Hussein, Waleed M., Rawi, Mohamad F. M., Hartley-Tassell, Lauren E., Day, Christopher J., Jennings, Michael P., Toth, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988166/
https://www.ncbi.nlm.nih.gov/pubmed/24736570
http://dx.doi.org/10.1371/journal.pone.0095024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988166/
https://www.ncbi.nlm.nih.gov/pubmed/24736570
http://dx.doi.org/10.1371/journal.pone.0095024

Ejemplares similares