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Combined Use of the Canine Adenovirus-2 and DREADD-Technology to Activate Specific Neural Pathways In Vivo

We here describe a technique to transiently activate specific neural pathways in vivo. It comprises the combined use of a CRE-recombinase expressing canine adenovirus-2 (CAV-2) and an adeno-associated virus (AAV-hSyn-DIO-hM(3)D(G(q))-mCherry) that contains the floxed inverted sequence of the designe...

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Detalles Bibliográficos
Autores principales: Boender, Arjen J., de Jong, Johannes W., Boekhoudt, Linde, Luijendijk, Mieneke C. M., van der Plasse, Geoffrey, Adan, Roger A. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988196/
https://www.ncbi.nlm.nih.gov/pubmed/24736748
http://dx.doi.org/10.1371/journal.pone.0095392