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Genetic and Infectious Profiles Influence Cerebrospinal Fluid IgG Abnormality in Japanese Multiple Sclerosis Patients

BACKGROUND: Abnormal intrathecal synthesis of IgG, reflected by cerebrospinal fluid (CSF) oligoclonal IgG bands (OBs) and increased IgG index, is much less frequently observed in Japanese multiple sclerosis (MS) cohorts compared with Western cohorts. We aimed to clarify whether genetic and common in...

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Detalles Bibliográficos
Autores principales: Yoshimura, Satoshi, Isobe, Noriko, Matsushita, Takuya, Masaki, Katsuhisa, Sato, Shinya, Kawano, Yuji, Ochi, Hirofumi, Kira, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988235/
https://www.ncbi.nlm.nih.gov/pubmed/24736746
http://dx.doi.org/10.1371/journal.pone.0095367