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Mice Deficient in Cryptochrome 1 (Cry1(−/−)) Exhibit Resistance to Obesity Induced by a High-Fat Diet

Disruption of circadian clock enhances the risk of metabolic syndrome, obesity, and type 2 diabetes. Circadian clocks rely on a highly regulated network of transcriptional and translational loops that drive clock-controlled gene expression. Among these transcribed clock genes are cryptochrome (CRY)...

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Detalles Bibliográficos
Autores principales: Griebel, Guy, Ravinet-Trillou, Christine, Beeské, Sandra, Avenet, Patrick, Pichat, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988402/
https://www.ncbi.nlm.nih.gov/pubmed/24782829
http://dx.doi.org/10.3389/fendo.2014.00049