A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids

There is evidence that tRNA bodies have evolved to reduce differences between aminoacyl-tRNAs in their affinity to EF-Tu. Here, we study the kinetics of incorporation of L-amino acids (AAs) Phe, Ala allyl-glycine (aG), methyl-serine (mS), and biotinyl-lysine (bK) using a tRNA(Ala)-based body (tRNA(A...

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Detalles Bibliográficos
Autores principales: Ieong, Ka-Weng, Pavlov, Michael Y., Kwiatkowski, Marek, Ehrenberg, Måns, Forster, Anthony C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988565/
https://www.ncbi.nlm.nih.gov/pubmed/24671767
http://dx.doi.org/10.1261/rna.042234.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988565/
https://www.ncbi.nlm.nih.gov/pubmed/24671767
http://dx.doi.org/10.1261/rna.042234.113

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