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Prevalent RNA recognition motif duplication in the human genome

The sequence-specific recognition of RNA by proteins is mediated through various RNA binding domains, with the RNA recognition motif (RRM) being the most frequent and present in >50% of RNA-binding proteins (RBPs). Many RBPs contain multiple RRMs, and it is unclear how each RRM contributes to the...

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Detalles Bibliográficos
Autores principales: Tsai, Yihsuan S., Gomez, Shawn M., Wang, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988571/
https://www.ncbi.nlm.nih.gov/pubmed/24667216
http://dx.doi.org/10.1261/rna.044081.113