RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABA(B)R-GIRK signaling

In the hippocampus, the inhibitory neurotransmitter GABA shapes the activity of the output pyramidal neurons and plays important role in cognition. Most of its inhibitory effects are mediated by signaling from GABAB receptor to the G protein-gated Inwardly-rectifying K+ (GIRK) channels. Here, we sho...

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Detalles Bibliográficos
Autores principales: Ostrovskaya, Olga, Xie, Keqiang, Masuho, Ikuo, Fajardo-Serrano, Ana, Lujan, Rafael, Wickman, Kevin, Martemyanov, Kirill A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988575/
https://www.ncbi.nlm.nih.gov/pubmed/24755289
http://dx.doi.org/10.7554/eLife.02053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988575/
https://www.ncbi.nlm.nih.gov/pubmed/24755289
http://dx.doi.org/10.7554/eLife.02053

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