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Cloning, expression, purification and characterisation of Erwinia carotovora L-asparaginase in Escherichia coli
BACKGROUND: For the past 30 years, bacterial L-asparaginases have been used as therapeutic agents in the treatment of acute childhood lymphoblastic leukemia. It is found in a variety of organisms such as microbes, plants and mammals. Their intrinsic low-rate glutaminase activity, however, causes ser...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988593/ https://www.ncbi.nlm.nih.gov/pubmed/24761390 http://dx.doi.org/10.4103/2277-9175.127995 |