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Hairpin DNA Sequences Bound Strongly by Bleomycin Exhibit Enhanced Double-Strand Cleavage

[Image: see text] Clinically used bleomycin A(5) has been employed in a study of double-strand cleavage of a library of 10 hairpin DNAs originally selected on the basis of their strong binding to bleomycin. Each of the DNAs underwent double-strand cleavage at more than one site, and all of the cleav...

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Detalles Bibliográficos
Autores principales: Roy, Basab, Hecht, Sidney M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988684/
https://www.ncbi.nlm.nih.gov/pubmed/24548300
http://dx.doi.org/10.1021/ja500414a