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Coilin association with Box C/D scaRNA suggests a direct role for the Cajal body marker protein in scaRNP biogenesis

Spliceosomal small nuclear ribonucleoproteins (snRNPs) are enriched in the Cajal body (CB). Guide RNAs, known as small Cajal body-specific RNAs (scaRNAs), direct modification of the small nuclear RNA (snRNA) component of the snRNP. The protein WRAP53 binds a sequence motif (the CAB box) found in man...

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Detalles Bibliográficos
Autores principales: Enwerem, Isioma I., Velma, Venkatramreddy, Broome, Hanna J., Kuna, Marija, Begum, Rowshan A., Hebert, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988793/
https://www.ncbi.nlm.nih.gov/pubmed/24659245
http://dx.doi.org/10.1242/bio.20147443