Assisted protein folding at low temperature: evolutionary adaptation of the Antarctic fish chaperonin CCT and its client proteins

Eukaryotic ectotherms of the Southern Ocean face energetic challenges to protein folding assisted by the cytosolic chaperonin CCT. We hypothesize that CCT and its client proteins (CPs) have co-evolved molecular adaptations that facilitate CCT–CP interaction and the ATP-driven folding cycle at low te...

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Detalles Bibliográficos
Autores principales: Cuellar, Jorge, Yébenes, Hugo, Parker, Sandra K., Carranza, Gerardo, Serna, Marina, Valpuesta, José María, Zabala, Juan Carlos, Detrich, H. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988795/
https://www.ncbi.nlm.nih.gov/pubmed/24659247
http://dx.doi.org/10.1242/bio.20147427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988795/
https://www.ncbi.nlm.nih.gov/pubmed/24659247
http://dx.doi.org/10.1242/bio.20147427

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