Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival

Sustained cellular function and viability of high-energy demanding post-mitotic cells rely on the continuous supply of ATP. The utilization of mitochondrial oxidative phosphorylation for efficient ATP generation is a function of oxygen levels. As such, oxygen deprivation, in physiological or patholo...

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Detalles Bibliográficos
Autores principales: Khacho, Mireille, Tarabay, Michelle, Patten, David, Khacho, Pamela, MacLaurin, Jason G., Guadagno, Jennifer, Bergeron, Richard, Cregan, Sean P., Harper, Mary-Ellen, Park, David S., Slack, Ruth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988820/
https://www.ncbi.nlm.nih.gov/pubmed/24686499
http://dx.doi.org/10.1038/ncomms4550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988820/
https://www.ncbi.nlm.nih.gov/pubmed/24686499
http://dx.doi.org/10.1038/ncomms4550

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