Cargando…

D-Glucosamine supplementation extends life span of nematodes and of ageing mice

D-Glucosamine (GlcN) is a freely available and commonly used dietary supplement potentially promoting cartilage health in humans, which also acts as an inhibitor of glycolysis. Here we show that GlcN, independent of the hexosamine pathway, extends Caenorhabditis elegans life span by impairing glucos...

Descripción completa

Detalles Bibliográficos
Autores principales: Weimer, Sandra, Priebs, Josephine, Kuhlow, Doreen, Groth, Marco, Priebe, Steffen, Mansfeld, Johannes, Merry, Troy L., Dubuis, Sébastien, Laube, Beate, Pfeiffer, Andreas F., Schulz, Tim J., Guthke, Reinhard, Platzer, Matthias, Zamboni, Nicola, Zarse, Kim, Ristow, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988823/
https://www.ncbi.nlm.nih.gov/pubmed/24714520
http://dx.doi.org/10.1038/ncomms4563