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D-Glucosamine supplementation extends life span of nematodes and of ageing mice
D-Glucosamine (GlcN) is a freely available and commonly used dietary supplement potentially promoting cartilage health in humans, which also acts as an inhibitor of glycolysis. Here we show that GlcN, independent of the hexosamine pathway, extends Caenorhabditis elegans life span by impairing glucos...
Autores principales: | Weimer, Sandra, Priebs, Josephine, Kuhlow, Doreen, Groth, Marco, Priebe, Steffen, Mansfeld, Johannes, Merry, Troy L., Dubuis, Sébastien, Laube, Beate, Pfeiffer, Andreas F., Schulz, Tim J., Guthke, Reinhard, Platzer, Matthias, Zamboni, Nicola, Zarse, Kim, Ristow, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988823/ https://www.ncbi.nlm.nih.gov/pubmed/24714520 http://dx.doi.org/10.1038/ncomms4563 |
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