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Dual Control of Yen1 Nuclease Activity and Cellular Localization by Cdk and Cdc14 Prevents Genome Instability

The careful orchestration of cellular events such as DNA replication, repair, and segregation is essential for equal distribution of the duplicated genome into two daughter cells. To ensure that persistent recombination intermediates are resolved prior to cell division, the Yen1 Holliday junction re...

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Detalles Bibliográficos
Autores principales: Blanco, Miguel G., Matos, Joao, West, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988869/
https://www.ncbi.nlm.nih.gov/pubmed/24631285
http://dx.doi.org/10.1016/j.molcel.2014.02.011