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A Splicing-Dependent Transcriptional Checkpoint Associated with Prespliceosome Formation
There is good evidence for functional interactions between splicing and transcription in eukaryotes, but how and why these processes are coupled remain unknown. Prp5 protein (Prp5p) is an RNA-stimulated adenosine triphosphatase (ATPase) required for prespliceosome formation in yeast. We demonstrate...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988880/ https://www.ncbi.nlm.nih.gov/pubmed/24560925 http://dx.doi.org/10.1016/j.molcel.2014.01.017 |