A phospha-oseltamivir–biotin conjugate as a strong and selective adhesive for the influenza virus

We present the synthesis and application of a molecule containing both the powerful influenza neuraminidase (NA) inhibitor phospha-oseltamivir and d-biotin, connected via an undecaethylene glycol spacer. It inhibits influenza virus neuraminidase (from the H3N2 X31 virus) in the same range as oseltam...

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Detalles Bibliográficos
Autores principales: Streicher, Hansjörg, Martin, Stephen R., Coombs, Peter J., McCauley, John, Neill-Hall, David, Stanley, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988921/
https://www.ncbi.nlm.nih.gov/pubmed/24594352
http://dx.doi.org/10.1016/j.bmcl.2014.02.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988921/
https://www.ncbi.nlm.nih.gov/pubmed/24594352
http://dx.doi.org/10.1016/j.bmcl.2014.02.021

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