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The gut hormone glucagon-like peptide-1 produced in brain: is this physiologically relevant?
Glucagon-like peptide-1 (GLP-1) is both a peripherally expressed incretin and a centrally active neuropeptide. Brain derived GLP-1, produced in preproglucagon (PPG) neurons located in the nucleus of the solitary tract (NTS) and projecting to numerous brain regions, is ideally placed to activate cent...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988995/ https://www.ncbi.nlm.nih.gov/pubmed/24075717 http://dx.doi.org/10.1016/j.coph.2013.09.006 |