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Characterization of altered intrinsic excitability in hippocampal CA1 pyramidal cells of the Aβ-overproducing PDAPP mouse()

Transgenic mice that accumulate Aβ peptides in the CNS are commonly used to interrogate functional consequences of Alzheimer's disease-associated amyloidopathy. In addition to changes to synaptic function, there is also growing evidence that changes to intrinsic excitability of neurones can ari...

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Detalles Bibliográficos
Autores principales: Kerrigan, T.L., Brown, J.T., Randall, A.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989024/
https://www.ncbi.nlm.nih.gov/pubmed/24055500
http://dx.doi.org/10.1016/j.neuropharm.2013.09.004