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The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: A novel possible model of OCD()

Excessive checking is a common, debilitating symptom of obsessive-compulsive disorder (OCD). In an established rodent model of OCD checking behaviour, quinpirole (dopamine D2/3-receptor agonist) increased checking in open-field tests, indicating dopaminergic modulation of checking-like behaviours. W...

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Detalles Bibliográficos
Autores principales: Eagle, Dawn M., Noschang, Cristie, d’Angelo, Laure-Sophie Camilla, Noble, Christie A., Day, Jacob O., Dongelmans, Marie Louise, Theobald, David E., Mar, Adam C., Urcelay, Gonzalo P., Morein-Zamir, Sharon, Robbins, Trevor W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989029/
https://www.ncbi.nlm.nih.gov/pubmed/24406720
http://dx.doi.org/10.1016/j.bbr.2013.12.040