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Mendelian randomization in health research: Using appropriate genetic variants and avoiding biased estimates()

Mendelian randomization methods, which use genetic variants as instrumental variables for exposures of interest to overcome problems of confounding and reverse causality, are becoming widespread for assessing causal relationships in epidemiological studies. The main purpose of this paper is to demon...

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Detalles Bibliográficos
Autores principales: Taylor, Amy E., Davies, Neil M., Ware, Jennifer J., VanderWeele, Tyler, Smith, George Davey, Munafò, Marcus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989031/
https://www.ncbi.nlm.nih.gov/pubmed/24388127
http://dx.doi.org/10.1016/j.ehb.2013.12.002