Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation

Chromosomal instability is a hallmark of human cancer cells, but its role in carcinogenesis remains poorly resolved. Insights into this role have emerged from studies on the tumour suppressor BRCA2, whose inactivation in human cancers causes chromosomal instability through the loss of essential func...

Descripción completa

Detalles Bibliográficos
Autores principales: Cassidy, Liam D., Liau, Siong-Seng, Venkitaraman, Ashok R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989051/
https://www.ncbi.nlm.nih.gov/pubmed/24268522
http://dx.doi.org/10.1016/j.molonc.2013.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989051/
https://www.ncbi.nlm.nih.gov/pubmed/24268522
http://dx.doi.org/10.1016/j.molonc.2013.10.005

Ejemplares similares