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Treg and CTLA-4: Two intertwining pathways to immune tolerance
Both the CTLA-4 pathway and regulatory T cells (Treg) are essential for the control of immune homeostasis. Their therapeutic relevance is highlighted by the increasing use of anti-CTLA-4 antibody in tumor therapy and the development of Treg cell transfer strategies for use in autoimmunity and transp...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Academic Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989116/ https://www.ncbi.nlm.nih.gov/pubmed/23849743 http://dx.doi.org/10.1016/j.jaut.2013.06.006 |