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Treg and CTLA-4: Two intertwining pathways to immune tolerance

Both the CTLA-4 pathway and regulatory T cells (Treg) are essential for the control of immune homeostasis. Their therapeutic relevance is highlighted by the increasing use of anti-CTLA-4 antibody in tumor therapy and the development of Treg cell transfer strategies for use in autoimmunity and transp...

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Detalles Bibliográficos
Autor principal:	Walker, Lucy S.K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989116/ https://www.ncbi.nlm.nih.gov/pubmed/23849743 http://dx.doi.org/10.1016/j.jaut.2013.06.006

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