Stiffness-Activated GEF-H1 Expression Exacerbates LPS-Induced Lung Inflammation

Acute lung injury (ALI) is accompanied by decreased lung compliance. However, a role of tissue mechanics in modulation of inflammation remains unclear. We hypothesized that bacterial lipopolysacharide (LPS) stimulates extracellular matrix (ECM) production and vascular stiffening leading to stiffness...

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Detalles Bibliográficos
Autores principales: Mambetsariev, Isa, Tian, Yufeng, Wu, Tinghuai, Lavoie, Tera, Solway, Julian, Birukov, Konstantin G., Birukova, Anna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989185/
https://www.ncbi.nlm.nih.gov/pubmed/24739883
http://dx.doi.org/10.1371/journal.pone.0092670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989185/
https://www.ncbi.nlm.nih.gov/pubmed/24739883
http://dx.doi.org/10.1371/journal.pone.0092670

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