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Proteinase-Activated Receptor 1 (PAR1) Regulates Leukemic Stem Cell Functions

External signals that are mediated by specific receptors determine stem cell fate. The thrombin receptor PAR1 plays an important role in haemostasis, thrombosis and vascular biology, but also in tumor biology and angiogenesis. Its expression and function in hematopoietic stem cells is largely unknow...

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Detalles Bibliográficos
Autores principales: Bäumer, Nicole, Krause, Annika, Köhler, Gabriele, Lettermann, Stephanie, Evers, Georg, Hascher, Antje, Bäumer, Sebastian, Berdel, Wolfgang E., Müller-Tidow, Carsten, Tickenbrock, Lara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989293/
https://www.ncbi.nlm.nih.gov/pubmed/24740120
http://dx.doi.org/10.1371/journal.pone.0094993